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La Roche-Posay Effaclar Duo+M is an advanced anti-blemish moisturizer developed with microbiome science. Its upgraded formula combines LHA, Niacinamide, and Piroctone Olamine to fight blemishes at the source, reduce post-acne marks, and restore a clearer, healthier-looking complexion. Non-comedogenic and dermatologist-tested, this lightweight gel-cream is suitable for oily and acne-prone skin and can be used as a daily moisturizer or targeted spot treatment.
Apply morning and/or evening to a clean face and neck. Can be used as a daily moisturizer or as a targeted treatment on blemish-prone areas. Follow with SPF in the morning. For external use only. Avoid contact with eyes.
Key actives include LHA (Lipo-Hydroxy Acid), Niacinamide (Vitamin B3), Piroctone Olamine, and La Roche-Posay Thermal Spring Water. Refer to product packaging for the complete and most up-to-date ingredient list.
| Brand | La Roche-Posay |
|---|---|
| Product Type | Moisturizer |
| Size | 40ml |
| Suitable For | General use |
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product.

Pharmacist-recommended products that work well together
Yes, it's designed to target blemishes and impurities while supporting the skin's natural balance.
Apply morning and/or evening to a clean face and neck, either as a daily moisturiser or on blemish-prone areas.
Yes, follow with an SPF in the morning.
It's designed to treat blemishes while still moisturising, but introduce it gradually if your skin is sensitive.
Check with your doctor or pharmacist before combining with other acne treatments.